BDBM344832 1-(3-cyclopentyl-2-::1-(3-cyclopentyl-2-oxopropyl)-3-[1-(2-fluorophenyl)-1H-indazol-4-yl]imidazolidin-2-one::US9783527, Example 134

SMILES Fc1ccccc1-n1ncc2c(cccc12)N1CCN(CC(=O)CC2CCCC2)C1=O

InChI Key InChIKey=LBMBMAUWSDCNSE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344832   

TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

US Patent
LigandPNGBDBM344832(1-(3-cyclopentyl-2-oxopropyl)-3-[1-(2-fluorophenyl...)
Affinity DataIC50: 1.26E+3nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent