BDBM344922 1-[1-(2-fluorophenyl)-1H-::1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-[(3S)-tetrahydrofuran-3-yl]imidazolidin-2-one::US9783527, Example 224

SMILES Fc1ccccc1-n1ncc2c(cccc12)N1CCN([C@H]2CCOC2)C1=O

InChI Key InChIKey=RNYKFTVSEJRRNB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344922   

TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

US Patent
LigandPNGBDBM344922(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-[(3S)-tet...)
Affinity DataIC50: 3.60E+3nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent