BDBM344951 1-[1-(2,4-difluorophenyl)-::1-[1-(2,4-difluorophenyl)-1H-indazol-4-yl]-3-[(1R)-1-(3-methyl-1,2,4-oxadiazol-5-yl)ethyl]imidazolidin-2-one::US9783527, Example 253

SMILES C[C@@H](N1CCN(C1=O)c1cccc2n(ncc12)-c1ccc(F)cc1F)c1nc(C)no1

InChI Key InChIKey=ZGBAMWRREZACCU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344951   

TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

US Patent
LigandPNGBDBM344951(1-[1-(2,4-difluorophenyl)-1H-indazol-4-yl]-3-[(1R)...)
Affinity DataIC50: 932nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent