BDBM345011 1-({3-[1-(2-fluorophenyl)-::1-({3-[1-(2-fluorophenyl)-1H-indazol-4-yl]-2-oxoimidazolidin-1-yl}acetyl)azepan-4-one::US9783527, Example 313

SMILES Fc1ccccc1-n1ncc2c(cccc12)N1CCN(CC(=O)N2CCCC(=O)CC2)C1=O

InChI Key InChIKey=NBYPYZVXLKVKHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 345011   

TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM345011(1-({3-[1-(2-fluorophenyl)- | 1-({3-[1-(2-fluorophe...)
Affinity DataIC50:  3.25E+3nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM345011(1-({3-[1-(2-fluorophenyl)- | 1-({3-[1-(2-fluorophe...)
Affinity DataIC50:  2.72E+3nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent