BDBM34571 6,7-bis(oxidanyl)chromen-2-one::6,7-dihydroxy-1-benzopyran-2-one::6,7-dihydroxychromen-2-one::CHEMBL244743::MLS000069479::SMR000059055::cid_5281416::esculetin

SMILES: c1c2c(cc(c1O)O)OC(=O)C=C2

InChI Key: InChIKey=ILEDWLMCKZNDJK-UHFFFAOYSA-N

Data: 6 KI  14 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 34571   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mannose-6-phosphate isomerase (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Sorbitol dehydrogenase (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B1 (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Xanthine dehydrogenase/oxidase (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Xanthine dehydrogenase/oxidase (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Maltase-glucoamylase (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 5B (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sortase family protein (Staphylococcus aureus)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage migration inhibitory factor (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Large T antigen (SV40)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mannose-6-phosphate isomerase (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.4	23
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Carbonic anhydrase 12 (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 1 (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage migration inhibitory factor (Human)	BDBM34571 (6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...) Show SMILES Show InChI	GoogleScholar	UniChem		1.84E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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