BDBM34572 BRIMONIDINE::CHEMBL844::MLS000069370::SMR000058355::UK 14,304::cid_2435

SMILES: c1cc(c(c2c1nccn2)Br)NC3=NCCN3

InChI Key: InChIKey=XYLJNLCSTIOKRM-UHFFFAOYSA-N

Data: 18 KI  4 IC50  8 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 34572   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2B adrenergic receptor (Rat)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.617	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.5	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
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Mannose-6-phosphate isomerase (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.4	23
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Alpha-2A adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.10	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.40	n/a	n/a	n/a	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a
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G protein-activated inward rectifier potassium channel 1 (Rat)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.0372	n/a	n/a	n/a	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (North American opossum)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Mouse)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		43.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (Rat)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		214	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Pig)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		479	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		955	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM34572 (UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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