BDBM345720 3-Methyl-butane-1-sulfonic acid [2- (2-chloro-6-fluoro-3-methyl- phenoxy)-6-(1-methyl-6-oxo-1,6- dihydro-pyridin-3-yl)-pyrimidin-4- yl]-amide::US10202360, Example 265

SMILES CC(C)CCS(=O)(=O)Nc1cc(nc(Oc2c(F)ccc(C)c2Cl)n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=CUCCKNLPLQCJCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345720   

TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM345720(3-Methyl-butane-1-sulfonic acid [2- (2-chloro-6-fl...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent