BDBM3489 6-arylpyrido[2,3-d]pyrimidine deriv. 71::N-[6-(2,6-Dichloro-phenyl)-2-(3-diethylaminopropylamino)-pyrido[2,3-d]pyrimidin-7-yl]-3,3-dimethylbutyramide::N-[6-(2,6-dichlorophenyl)-2-{[3-(diethylamino)propyl]amino}pyrido[2,3-d]pyrimidin-7-yl]-3,3-dimethylbutanamide

SMILES CCN(CC)CCCNc1ncc2cc(c(NC(=O)CC(C)(C)C)nc2n1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=IIROBNCWLNKPGG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3489   

LigandPNGBDBM3489(N-[6-(2,6-dichlorophenyl)-2-{[3-(diethylamino)prop...)
Affinity DataIC50: 1.90E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed
LigandPNGBDBM3489(N-[6-(2,6-dichlorophenyl)-2-{[3-(diethylamino)prop...)
Affinity DataIC50: 2.70E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed
LigandPNGBDBM3489(N-[6-(2,6-dichlorophenyl)-2-{[3-(diethylamino)prop...)
Affinity DataIC50: 5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed