BDBM349575 US10207991, Ex. Cpd. No. 100::US10611728, Example Compound 100::US11691947, Example 100

SMILES COc1ccc(CCC(C)(C)N2Cc3cccc(C(=O)N4CCNCC4)c3C2)cc1OC

InChI Key InChIKey=MXAUURQBNVRGPJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 349575   

TargetSigma intracellular receptor 2(Rat)
Cognition Therapeutics

US Patent
LigandPNGBDBM349575(US10207991, Ex. Cpd. No. 100 | US10611728, Example...)
Affinity DataKi:  1.00E+4nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
US Patent

TargetSigma intracellular receptor 2(Human)
Cognition Therapeutics

US Patent
LigandPNGBDBM349575(US10207991, Ex. Cpd. No. 100 | US10611728, Example...)
Affinity DataKi:  1.00E+4nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetSigma intracellular receptor 2(Human)
Cognition Therapeutics

US Patent
LigandPNGBDBM349575(US10207991, Ex. Cpd. No. 100 | US10611728, Example...)
Affinity DataKi:  1.00E+4nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent

TargetSigma intracellular receptor 2(Human)
Cognition Therapeutics

US Patent
LigandPNGBDBM349575(US10207991, Ex. Cpd. No. 100 | US10611728, Example...)
Affinity DataKi:  1.00E+4nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent