BDBM349616 (3-(4-(2- (cyclohexylamino)ethyl)phenoxy)-6- hydroxybenzo[b]thiophen-2-yl)(4-fluoro- 2,6-dimethylphenyl)methanone::US10208011, Compound 110::US10981887, Compound 110

SMILES Cc1cc(F)cc(C)c1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(CCNC2CCCCC2)cc1

InChI Key InChIKey=AVFYQZQDGGKXBE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 349616   

TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
G1 Therapeutics

US Patent
LigandPNGBDBM349616((3-(4-(2- (cyclohexylamino)ethyl)phenoxy)-6- hydro...)
Affinity DataIC50: <1.00E+3nMAssay Description:A screening strategy was implemented utilizing an In-Cell Western assay to measure their ability to degrade the estrogen receptor in vitro. MCF7 cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
G1 Therapeutics

US Patent
LigandPNGBDBM349616((3-(4-(2- (cyclohexylamino)ethyl)phenoxy)-6- hydro...)
Affinity DataIC50: <1.00E+3nMAssay Description:All reagents used in this assay was supplied in the Human ERα Reporter Assay by Indigo Biosciences #IB00401. In an effort to screen selective es...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
G1 Therapeutics

US Patent
LigandPNGBDBM349616((3-(4-(2- (cyclohexylamino)ethyl)phenoxy)-6- hydro...)
Affinity DataIC50: <1.00E+3nMAssay Description:A screening strategy was implemented utilizing an In-Cell Western assay to measure their ability to degrade the estrogen receptor in vitro. MCF7 cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
G1 Therapeutics

US Patent
LigandPNGBDBM349616((3-(4-(2- (cyclohexylamino)ethyl)phenoxy)-6- hydro...)
Affinity DataIC50: <1.00E+3nMAssay Description:All reagents used in this assay was supplied in the Human ERα Reporter Assay by Indigo Biosciences # IB00401. In an effort to screen selective e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent