BDBM349662 2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy}pyridin-2-yl)piperidin-1-yl]methyl}-1-[(2S)-oxetan-2-ylmethyl]-1H-benzimidazole-6-carboxylic acid::US10208019, Example 1A-09::US10208019, Example 4A-01

SMILES: c1cc(nc(c1)OCc2ccc(cc2F)C#N)C3CCN(CC3)Cc4nc5ccc(cc5n4C[C@@H]6CCO6)C(=O)O

InChI Key: InChIKey=HYBAKUMPISVZQP-UHFFFAOYSA-N

Data: 2 KI  2 IC50  14 EC50

PDB links: 4 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 349662   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glucagon-like peptide 1 receptor (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.710	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glucagon-like peptide 1 receptor (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glucagon-like peptide 1 receptor (Mouse)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
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Glucagon-like peptide 1 receptor (Rat)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
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Glucagon-like peptide 1 receptor (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	490	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Glucagon-like peptide 1 receptor (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	760	n/a	n/a	n/a	n/a
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Glucagon-like peptide 1 receptor (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.950	n/a	n/a	n/a	n/a
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Glucagon-like peptide 1 receptor (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Glucagon-like peptide 1 receptor (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Glucagon-like peptide 1 receptor (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Glucagon-like peptide 1 receptor (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.710	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Glucagon-like peptide 1 receptor (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glucagon-like peptide 1 receptor (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Glucagon-like peptide 1 receptor (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Glucagon-like peptide 1 receptor (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Glucagon-like peptide 1 receptor (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucagon-like peptide 1 receptor (Human)	BDBM349662 (2-{[4-(6-{[(4-cyano-2-fluorophenyl)(methyl-d2)]oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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