BDBM350073 6-(3-amino-6-(1-(1- hydroxy-2- methylpropan-2-yl)-1H- pyrazol-4-yl)pyrazin-2- yl)-2-(2,6-dichloro-3,5- dimethoxyphenyl)pyridazin- 3(2H)-one::US10208024, Example 72::US10766881, Example 72
SMILES COc1cc(OC)c(Cl)c(c1Cl)-n1nc(ccc1=O)-c1nc(cnc1N)-c1cnn(c1)C(C)(C)CO
InChI Key InChIKey=KSYWMSVHBYZLJH-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 350073
Affinity DataIC50: 7.30nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Affinity DataIC50: 7.30nMAssay Description:To measure FGFR1 kinase activity, 200 pM His-tagged recombinant human FGFR1 catalytic domain (amino acids 308-731) (Life Technologies Cat. No. PR4660...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair