BDBM35051 benzothienopyrimidinone deriv., 3b

SMILES Clc1ccc(Cl)c2c3nc[nH]c(=O)c3sc12

InChI Key InChIKey=DJUSDFVEBBYFFL-UHFFFAOYSA-N

Data  3 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 35051   

TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM35051(benzothienopyrimidinone deriv., 3b)
Affinity DataKi:  11nM ΔG°:  -10.8kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM35051(benzothienopyrimidinone deriv., 3b)
Affinity DataKi:  130nM ΔG°:  -9.39kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM35051(benzothienopyrimidinone deriv., 3b)
Affinity DataKi:  164nM ΔG°:  -9.25kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed