BDBM350568 N-(4-bromophenyl) spiro[bicyclo[2.2.1]heptane- 7,1'-cyclopropane]-2,3- dicarboxamide::US10208071, Compound 30::US10434112, Compound 45

SMILES: NC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1

InChI Key: InChIKey=JXDQSNBDUYHJHD-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM350568 (N-(4-bromophenyl) spiro[bicyclo[2.2.1]heptane- 7,1...) Show SMILES NC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1 Show InChI InChI=1S/C17H19BrN2O2/c18-9-1-3-10(4-2-9)20-16(22)14-12-6-5-11(13(14)15(19)21)17(12)7-8-17/h1-4,11-14H,5-8H2,(H2,19,21)(H,20,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
Allergan Inc US Patent					Assay Description HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...				US Patent US10208071 (2019) BindingDB Entry DOI: 10.7270/Q2TH8PT9
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM350568 (N-(4-bromophenyl) spiro[bicyclo[2.2.1]heptane- 7,1...) Show SMILES NC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1 Show InChI InChI=1S/C17H19BrN2O2/c18-9-1-3-10(4-2-9)20-16(22)14-12-6-5-11(13(14)15(19)21)17(12)7-8-17/h1-4,11-14H,5-8H2,(H2,19,21)(H,20,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...				US Patent US10434112 (2019) BindingDB Entry DOI: 10.7270/Q2HX1G16
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM350568 (N-(4-bromophenyl) spiro[bicyclo[2.2.1]heptane- 7,1...) Show SMILES NC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1 Show InChI InChI=1S/C17H19BrN2O2/c18-9-1-3-10(4-2-9)20-16(22)14-12-6-5-11(13(14)15(19)21)17(12)7-8-17/h1-4,11-14H,5-8H2,(H2,19,21)(H,20,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...				US Patent US10434112 (2019) BindingDB Entry DOI: 10.7270/Q2HX1G16
					More data for this Ligand-Target Pair