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BDBM350568 N-(4-bromophenyl) spiro[bicyclo[2.2.1]heptane- 7,1'-cyclopropane]-2,3- dicarboxamide::US10208071, Compound 30::US10434112, Compound 45

SMILES: NC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1

InChI Key: InChIKey=JXDQSNBDUYHJHD-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350568   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350568
PNG
(N-(4-bromophenyl) spiro[bicyclo[2.2.1]heptane- 7,1...)
Show SMILES NC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1
Show InChI InChI=1S/C17H19BrN2O2/c18-9-1-3-10(4-2-9)20-16(22)14-12-6-5-11(13(14)15(19)21)17(12)7-8-17/h1-4,11-14H,5-8H2,(H2,19,21)(H,20,22)
PDB

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PC cid
PC sid
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US Patent
n/an/an/an/a 2.50E+3n/an/an/an/a



Allergan Inc

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10208071 (2019)


BindingDB Entry DOI: 10.7270/Q2TH8PT9
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350568
PNG
(N-(4-bromophenyl) spiro[bicyclo[2.2.1]heptane- 7,1...)
Show SMILES NC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1
Show InChI InChI=1S/C17H19BrN2O2/c18-9-1-3-10(4-2-9)20-16(22)14-12-6-5-11(13(14)15(19)21)17(12)7-8-17/h1-4,11-14H,5-8H2,(H2,19,21)(H,20,22)
PDB

NCI pathway
Reactome pathway
KEGG

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antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<1n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)


BindingDB Entry DOI: 10.7270/Q2HX1G16
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350568
PNG
(N-(4-bromophenyl) spiro[bicyclo[2.2.1]heptane- 7,1...)
Show SMILES NC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1
Show InChI InChI=1S/C17H19BrN2O2/c18-9-1-3-10(4-2-9)20-16(22)14-12-6-5-11(13(14)15(19)21)17(12)7-8-17/h1-4,11-14H,5-8H2,(H2,19,21)(H,20,22)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2.5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)


BindingDB Entry DOI: 10.7270/Q2HX1G16
More data for this
Ligand-Target Pair