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BDBM350892 3-(2-Bromophenyl)-2-cyclopropylmethylthio-4-oxo-3,4-dihydroquinazoline::US9796687, Compound 14

SMILES: Brc1ccccc1-n1c(SCC2CC2)nc2ccccc2c1=O

InChI Key: InChIKey=JZYSMPKYJVYWCY-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350892   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 7


(Homo sapiens (Human))
BDBM350892
PNG
(3-(2-Bromophenyl)-2-cyclopropylmethylthio-4-oxo-3,...)
Show SMILES Brc1ccccc1-n1c(SCC2CC2)nc2ccccc2c1=O
Show InChI InChI=1S/C18H15BrN2OS/c19-14-6-2-4-8-16(14)21-17(22)13-5-1-3-7-15(13)20-18(21)23-11-12-9-10-12/h1-8,12H,9-11H2
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a 9.44E+3n/an/an/an/an/an/a



Consejo Superior de Investigaciones Cientificas

US Patent


Assay Description
Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...


US Patent US9796687 (2017)


BindingDB Entry DOI: 10.7270/Q2NV9MDC
More data for this
Ligand-Target Pair