BDBM351326 1,4:3,6-dianhydro-2-O-[4-[(4-bromo-5-chloro- 2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol::US9796704, Entry 61

SMILES CO[C@H]1CO[C@@H]2[C@H](CO[C@H]12)Oc1cc2ncnc(Nc3cc(Cl)c(Br)cc3F)c2cc1OC

InChI Key InChIKey=UUILILXZMGYNLD-UWHLTILDSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 351326   

TargetEphrin type-B receptor 4(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351326(1,4:3,6-dianhydro-2-O-[4-[(4-bromo-5-chloro- 2-flu...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351326(1,4:3,6-dianhydro-2-O-[4-[(4-bromo-5-chloro- 2-flu...)
Affinity DataIC50:  1.05E+4nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351326(1,4:3,6-dianhydro-2-O-[4-[(4-bromo-5-chloro- 2-flu...)
Affinity DataIC50:  1.05E+4nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351326(1,4:3,6-dianhydro-2-O-[4-[(4-bromo-5-chloro- 2-flu...)
Affinity DataIC50:  1.05E+4nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351326(1,4:3,6-dianhydro-2-O-[4-[(4-bromo-5-chloro- 2-flu...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351326(1,4:3,6-dianhydro-2-O-[4-[(4-bromo-5-chloro- 2-flu...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351326(1,4:3,6-dianhydro-2-O-[4-[(4-bromo-5-chloro- 2-flu...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351326(1,4:3,6-dianhydro-2-O-[4-[(4-bromo-5-chloro- 2-flu...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351326(1,4:3,6-dianhydro-2-O-[4-[(4-bromo-5-chloro- 2-flu...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351326(1,4:3,6-dianhydro-2-O-[4-[(4-bromo-5-chloro- 2-flu...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351326(1,4:3,6-dianhydro-2-O-[4-[(4-bromo-5-chloro- 2-flu...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent