BDBM351652 N-(4-bromo-3-(4H-1,2,4-triazol-3-yl)thiophen-2-yl)-2-(5-(trifluoromethyl)quinolin-7-yl)acetamide::US9796706, Compound 96

SMILES FC(F)(F)c1cc(CC(=O)Nc2scc(Br)c2-c2nnc[nH]2)cc2ncccc12

InChI Key InChIKey=XQRZYWOHUXJXMF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 351652   

TargetMitogen-activated protein kinase 9(Human)
Imago Pharmaceuticals

US Patent
LigandPNGBDBM351652(US9796706, Compound 96 | N-(4-bromo-3-(4H-1,2,4-tr...)
Affinity DataIC50: 5.05E+3nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetMitogen-activated protein kinase 10(Human)
Imago Pharmaceuticals

US Patent
LigandPNGBDBM351652(US9796706, Compound 96 | N-(4-bromo-3-(4H-1,2,4-tr...)
Affinity DataIC50: 5.05E+3nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetMitogen-activated protein kinase 8(Human)
Imago Pharmaceuticals

US Patent
LigandPNGBDBM351652(US9796706, Compound 96 | N-(4-bromo-3-(4H-1,2,4-tr...)
Affinity DataIC50: 5.05E+3nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent