BDBM35168 indazole-benzimidazole, 4

SMILES CN1CCN(CC1)c1cccc2[nH]c(nc12)-c1n[nH]c2cc(ccc12)-c1ccc(O)cc1

InChI Key InChIKey=IAHVSHNBRRKKBX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35168   

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer

LigandPNGBDBM35168(indazole-benzimidazole, 4)
Affinity DataIC50:  13.3nMT: 2°CAssay Description:Active cyclin dependent kinase 2 (CDK2) activity was determined by measuring the phosphorylation of Histone type 3 (Sigma H5505), in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Pfizer

LigandPNGBDBM35168(indazole-benzimidazole, 4)
Affinity DataIC50:  5.60nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed