BDBM35255 2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin::2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin::2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine::CHEMBL285802::Nipolept::Zoleptil::zotepine

SMILES: CN(C)CCOC1=Cc2ccccc2Sc3c1cc(cc3)Cl

InChI Key: InChIKey=HDOZVRUNCMBHFH-UHFFFAOYSA-N

Data: 84 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 84 hits for monomerid = 35255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		0.620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		0.620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Rat)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		1.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 7 (Rat)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		1.78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Pig)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histamine H1 receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Histamine H1 receptor (Guinea pig)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Alpha-1A adrenergic receptor (Rat)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(4) dopamine receptor (Rat)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(3) dopamine receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Mouse)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rat)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1B (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1D (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M3 (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M4 (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Rat)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Human)	BDBM35255 (2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...) Show SMILES Show InChI	GoogleScholar	UniChem		140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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