BDBM3531 CHEMBL541586::CHEMBL94431::N-(3-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine::PD153035 Analog 30

SMILES: COc1cc2ncnc(Nc3cccc(F)c3)c2cc1OC

InChI Key: InChIKey=DFWBDVRBHHFDNZ-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 3531   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM3531 (CHEMBL541586 | N-(3-fluorophenyl)-6,7-dimethoxyqui...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM3531 (CHEMBL541586 | N-(3-fluorophenyl)-6,7-dimethoxyqui...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	90	n/a	n/a	n/a	n/a	7.6	22
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Tyrosine-protein kinase Lck (Human)	BDBM3531 (CHEMBL541586 | N-(3-fluorophenyl)-6,7-dimethoxyqui...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3531 (CHEMBL541586 | N-(3-fluorophenyl)-6,7-dimethoxyqui...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3531 (CHEMBL541586 | N-(3-fluorophenyl)-6,7-dimethoxyqui...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	31.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3531 (CHEMBL541586 | N-(3-fluorophenyl)-6,7-dimethoxyqui...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3531 (CHEMBL541586 | N-(3-fluorophenyl)-6,7-dimethoxyqui...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair