BDBM3532 CHEMBL540068::CHEMBL7917::N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine::PD153035 Analog 31

SMILES: COc1cc2c(cc1OC)ncnc2Nc3cccc(c3)Cl

InChI Key: InChIKey=GFNNBHLJANVSQV-UHFFFAOYSA-N

Data: 5 KI  27 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 3532   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.316	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26	n/a	n/a	n/a	n/a	n/a	n/a
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Fructose-1,6-bisphosphatase 1 (Pig)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Fructose-1,6-bisphosphatase 1 (Rat)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Fructose-1,6-bisphosphatase 1 (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-interacting serine/threonine-protein kinase 1 (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-ketoglutarate-dependent dioxygenase FTO (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1/ABL2 (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Mouse)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C alpha type (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	900	n/a	n/a	n/a	n/a	7.6	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		1.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		1.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		2.62E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		2.62E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (Human)	BDBM3532 (CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...) Show SMILES Show InChI	GoogleScholar	UniChem		2.63E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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