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BDBM35335 2-oxo-1,2-dihydropyridin-3-yl amide derivative, 7x

SMILES: COc1ccccc1CNC(=O)Cn1cccc(NCc2ccccc2)c1=O

InChI Key: InChIKey=QTOQOYFUKXTGRP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 35335   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM35335
PNG
(2-oxo-1,2-dihydropyridin-3-yl amide derivative, 7x)
Show SMILES COc1ccccc1CNC(=O)Cn1cccc(NCc2ccccc2)c1=O
Show InChI InChI=1S/C22H23N3O3/c1-28-20-12-6-5-10-18(20)15-24-21(26)16-25-13-7-11-19(22(25)27)23-14-17-8-3-2-4-9-17/h2-13,23H,14-16H2,1H3,(H,24,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.08E+5n/an/an/an/a7.222



Griffith University



Assay Description
RMGPa (Rabbit Muscle Glycogen Phosphorylase a) activity was measured in the direction of glycogen synthesis by the formation of inorganic phosphate f...


Bioorg Med Chem 17: 4724-33 (2009)


Article DOI: 10.1016/j.bmc.2009.04.049
BindingDB Entry DOI: 10.7270/Q2PR7TBG
More data for this
Ligand-Target Pair