BDBM3534 6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazolin-4-amine::CHEMBL316064::PD153035 Analog 34

SMILES: COc1cc2ncnc(Nc3cccc(c3)C(F)(F)F)c2cc1OC

InChI Key: InChIKey=KEQCEKUDWPXRRQ-UHFFFAOYSA-N

Data: 8 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 3534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM3534 (6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM3534 (6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.245	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM3534 (6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
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Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM3534 (6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM3534 (6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity protein kinase CLK1 (Human)	BDBM3534 (6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Rat)	BDBM3534 (6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 5 activator 1 (Human)	BDBM3534 (6,7-dimethoxy-N-[3-(trifluoromethyl)phenyl]quinazo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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