BDBM353645 US9796708, Example 877::{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-1-(methylsulfonyl)-1,2,3,6-tetrahydropyridin-2-yl}methanol

SMILES COc1ccc(F)cc1-c1ccnc2[nH]c(cc12)C1=CCN(C(CO)C1)S(C)(=O)=O

InChI Key InChIKey=UUKYPWDWKSCAMY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 353645   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Abbvie

US Patent
LigandPNGBDBM353645(US9796708, Example 877 | {4-[4-(5-fluoro-2-methoxy...)
Affinity DataIC50: 69nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent