BDBM3540 4-N-(3-bromophenyl)-7-N-methylquinazoline-4,7-diamine::4-[(3-Bromophenyl)amino]-7-(methylamino)quinazoline::CHEMBL92812::PD153035 Analog::PD153035 Analog 40

SMILES CNc1ccc2c(Nc3cccc(Br)c3)ncnc2c1

InChI Key InChIKey=NJCGPPRBJLJTPA-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 3540   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3540(4-N-(3-bromophenyl)-7-N-methylquinazoline-4,7-diam...)
Affinity DataIC50:  7nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
Protana

Curated by ChEMBL
LigandPNGBDBM3540(4-N-(3-bromophenyl)-7-N-methylquinazoline-4,7-diam...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of EPH receptor B2 using ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
Protana

Curated by ChEMBL
LigandPNGBDBM3540(4-N-(3-bromophenyl)-7-N-methylquinazoline-4,7-diam...)
Affinity DataKd:  2.19E+4nMAssay Description:Equilibrium binding constant for EPH receptor B2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3540(4-N-(3-bromophenyl)-7-N-methylquinazoline-4,7-diam...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed