BDBM354268 (2S,4R)-1-(2-(3-acetyl- 5-(2-methylpyrimidin- 5-yl)-1H-indazol-1- yl)acetyl)-N-(6- bromopyridin-2-yl)-4- fluoropyrrolidine-2- carboxamide::US10287301, Compound 165::US10822352, Comp No. 165::US9796741, cmp No. 165

SMILES: CC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccc(cc12)-c1cnc(C)nc1

InChI Key: InChIKey=PIBARDGJJAGJAJ-UHFFFAOYSA-N

Data: 6 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 354268   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Human)	BDBM354268 ((2S,4R)-1-(2-(3-acetyl- 5-(2-methylpyrimidin- 5-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Complement factor D (Human)	BDBM354268 ((2S,4R)-1-(2-(3-acetyl- 5-(2-methylpyrimidin- 5-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Complement factor D (Human)	BDBM354268 ((2S,4R)-1-(2-(3-acetyl- 5-(2-methylpyrimidin- 5-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Complement factor D (Human)	BDBM354268 ((2S,4R)-1-(2-(3-acetyl- 5-(2-methylpyrimidin- 5-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Complement factor D (Human)	BDBM354268 ((2S,4R)-1-(2-(3-acetyl- 5-(2-methylpyrimidin- 5-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Complement factor D (Human)	BDBM354268 ((2S,4R)-1-(2-(3-acetyl- 5-(2-methylpyrimidin- 5-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Complement factor D (Human)	BDBM354268 ((2S,4R)-1-(2-(3-acetyl- 5-(2-methylpyrimidin- 5-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair