BDBM354406 US9796719, Compound 74::tert-butyl-(1R,4S)- 5-(2-ethyl-3-((4-(4- fluorophenyl) thiazol-2- yl)(methyl)amino) imidazo[1,2- b]pyridazin-6-yl)- 2,5- diazabicyclo[2.2.1] heptane-2- carboxylate

SMILES CCc1nc2ccc(nn2c1N(C)c1nc(cs1)-c1ccc(F)cc1)N1C[C@H]2C[C@H]1CN2C(=O)OC(C)(C)C

InChI Key InChIKey=MAMWYFAATSLFLO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354406   

TargetAutotaxin(Human)
Galapagos

US Patent
LigandPNGBDBM354406(tert-butyl-(1R,4S)- 5-(2-ethyl-3-((4-(4- fluorophe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound IC50 values are determined in a fluorescent hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotax...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2019
Entry Details
US Patent