BDBM354407 1-((1R,4S)-5-(2- ethyl-3-((4-(4- fluorophenyl) thiazol-2- yl)(methyl)amino) imidazo[1,2- b]pyridazin-6-yl)- 2,5- diazabicyclo[2.2.1] heptan-2- yl)ethanone::US9796719, Compound 75

SMILES CCc1nc2ccc(nn2c1N(C)c1nc(cs1)-c1ccc(F)cc1)N1C[C@H]2C[C@H]1CN2C(C)=O

InChI Key InChIKey=MZHXFGKHZYKNLY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354407   

TargetAutotaxin(Human)
Galapagos

US Patent
LigandPNGBDBM354407(1-((1R,4S)-5-(2- ethyl-3-((4-(4- fluorophenyl) thi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound IC50 values are determined in a fluorescent hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotax...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2019
Entry Details
US Patent