BDBM354502 N-((1-(3-((5-cyano- 4-(4- fluorophenyl) thiazol-2- yl)(methyl)amino)- 2-ethylimidazo[1,2- b]pyridazin-6-yl)-3- hydroxypyrrolidin- 3- yl)methyl) isobutyramide::US9796719, Compound 170

SMILES CCc1nc2ccc(nn2c1N(C)c1nc(c(s1)C#N)-c1ccc(F)cc1)N1CCC(O)(CNC(=O)C(C)C)C1

InChI Key InChIKey=CDFRKTMKLUHCMI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354502   

TargetAutotaxin(Human)
Galapagos

US Patent
LigandPNGBDBM354502(N-((1-(3-((5-cyano- 4-(4- fluorophenyl) thiazol-2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound IC50 values are determined in a fluorescent hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotax...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2019
Entry Details
US Patent