BDBM355494 N-[(R)-(2,2-difluoro-1,3- benzodioxol-5-yl)(1- methylcyclopropyl)methyl]-6-oxo- 1,6-dihydro-2,2'-bipyrimidine-4- carboxamide::US9815796, Example 585

SMILES CC1(CC1)[C@@H](NC(=O)c1cc(=O)[nH]c(n1)-c1ncccn1)c1ccc2OC(F)(F)Oc2c1

InChI Key InChIKey=TYVHWXWISYRAEL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355494   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM355494(US9815796, Example 585 | N-[(R)-(2,2-difluoro-1,3-...)
Affinity DataKi:  39nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
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Date in BDB:
10/13/2019
Entry Details
US Patent