BDBM355499 N-[(1R)-1-(2,2-difluoro-1,3- benzodioxol-5-yl)propyl]-6-oxo- 1,6-dihydro-2,2'-bipyrimidine-4- carboxamide::US9815796, Example 590

SMILES CC[C@@H](NC(=O)c1cc(=O)[nH]c(n1)-c1ncccn1)c1ccc2OC(F)(F)Oc2c1

InChI Key InChIKey=CEIFFVSLXXMVDA-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355499   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM355499(US9815796, Example 590 | N-[(1R)-1-(2,2-difluoro-1...)
Affinity DataKi:  34nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
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Date in BDB:
10/13/2019
Entry Details
US Patent