BDBM355506 N-{1-[2-fluoro-4- (trifluoromethoxy)phenyl]-1- methylethyl}-2-methyl-6-oxo-1,6- dihydropyrimidine-4-carboxamide::US9815796, Example 597

SMILES Cc1nc(cc(=O)[nH]1)C(=O)NC(C)(C)c1ccc(OC(F)(F)F)cc1F

InChI Key InChIKey=PEROTGXJDNWJCJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355506   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM355506(US9815796, Example 597 | N-{1-[2-fluoro-4- (triflu...)
Affinity DataKi:  137nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
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Date in BDB:
10/13/2019
Entry Details
US Patent