BDBM355507 2-ethyl-N-{(1R)-1-[3-fluoro-4- (trifluoromethoxy)phenyl]ethyl}-6- oxo-1,6-dihydropyrimidine-4- carboxamide::US9815796, Example 598

SMILES CCc1nc(cc(=O)[nH]1)C(=O)N[C@H](C)c1ccc(OC(F)(F)F)c(F)c1

InChI Key InChIKey=XSALEQGDBRIXHF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355507   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM355507(US9815796, Example 598 | 2-ethyl-N-{(1R)-1-[3-fluo...)
Affinity DataKi:  3.70nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
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Date in BDB:
10/13/2019
Entry Details
US Patent