BDBM355508 2-ethyl-6-oxo-N-{(1R)-1-[4- (pentafluoro-lambda6- sulfanyl)phenyl]ethyl}-1,6- dihydropyrimidine-4-carboxamide::US9815796, Example 599

SMILES CCc1nc(cc(=O)[nH]1)C(=O)N[C@H](C)c1ccc(cc1)S(F)(F)(F)(F)F

InChI Key InChIKey=IUCXKZZNUXWTGS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355508   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM355508(US9815796, Example 599 | 2-ethyl-6-oxo-N-{(1R)-1-[...)
Affinity DataKi:  10nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
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Date in BDB:
10/13/2019
Entry Details
US Patent