BDBM3557 CHEMBL418967::N-(3-bromophenyl)-6,7-dipropoxyquinazolin-4-amine::PD153035 Analog 57

SMILES CCCOc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OCCC

InChI Key InChIKey=ZBOJKFDQWQBBHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3557   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM3557(CHEMBL418967 | N-(3-bromophenyl)-6,7-dipropoxyquin...)
Affinity DataIC50:  0.174nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM3557(CHEMBL418967 | N-(3-bromophenyl)-6,7-dipropoxyquin...)
Affinity DataIC50:  0.170nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed