BDBM355911 1-(7-(sec-butyl)-2- chloropyrazolo[1,5- a]pyrimidin-6-yl)-3- (5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-yl)urea::US10442808, Example 35::US9815842, Example 35

SMILES CCC(C)c1c(NC(=O)Nc2cnc(c(Cl)c2)-n2nccn2)cnc2cc(Cl)nn12

InChI Key InChIKey=BMJWTOZQYCEGJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 355911   

LigandPNGBDBM355911(1-(7-(sec-butyl)-2- chloropyrazolo[1,5- a]pyrimidi...)
Affinity DataIC50:  0.00300nMAssay Description:The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM355911(1-(7-(sec-butyl)-2- chloropyrazolo[1,5- a]pyrimidi...)
Affinity DataIC50:  0.00300nMAssay Description:IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent