BDBM355974 1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-yl)-3-(2- chloro-7-((1R,2R)- 1,2- dimethoxypropyl)py- razolo[1,5- a]pyrimidin-6-yl)urea::US10442808, Example 98::US9815842, Example 98

SMILES CO[C@H](C)[C@H](OC)c1c(NC(=O)Nc2cnc(c(Cl)c2)-n2nccn2)cnc2cc(Cl)nn12

InChI Key InChIKey=XKQLNDPUQSZBJW-QGHHPUGFSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 355974   

LigandPNGBDBM355974(1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...)
Affinity DataIC50:  0.00500nMAssay Description:The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM355974(1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-y...)
Affinity DataIC50:  0.00500nMAssay Description:IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...More data for this Ligand-Target Pair