BDBM356039 US9815846, Compound 39

SMILES OCc1ncc(NC(=O)c2ccc(c(c2)-c2ncccn2)C(F)(F)F)c(n1)-c1ccccc1

InChI Key InChIKey=HMSMJYZNVRURNE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356039   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM356039(US9815846, Compound 39)
Affinity DataIC50:  70nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent