BDBM356141 US9815846, Compound 141

SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2cc3C(=O)NCCc3nc2-c2ccccn2)c(F)cc1C(F)(F)F

InChI Key InChIKey=RGJMBYXDMBSBAF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356141   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM356141(US9815846, Compound 141)
Affinity DataIC50:  14nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent