BDBM35702 5H-1-benzazepin-5-ylidene acetamide, 10i

SMILES FC1(F)CCN(C(=O)c2ccc(cc2Cl)N2CCCC2)c2ccccc2\C1=C\C(=O)NCc1ccccn1

InChI Key InChIKey=JWRLDYGEOOQZNG-MOHJPFBDSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 35702   

TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM35702(5H-1-benzazepin-5-ylidene acetamide, 10i)
Affinity DataKi:  22nM ΔG°:  -10.4kcal/mole EC50:  3.13nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed