BDBM357272 2-(((1s,4s)-4-((5-(2- hydroxyethylthio)-4-(3- methoxyphenyl)-3-phenyl- 1H-pyrazol-1- yl)methyl)cyclohexyl) methoxy)acetic acid::US10214518, Compound 198::US11098034, Compound 198

SMILES COc1cccc(c1)-c1c(SCCO)n(C[C@@H]2CC[C@H](COCC(O)=O)CC2)nc1-c1ccccc1

InChI Key InChIKey=LQLBVRMQYUIDPG-OYRHEFFESA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357272   

TargetProstacyclin receptor(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM357272(2-(((1s,4s)-4-((5-(2- hydroxyethylthio)-4-(3- meth...)
Affinity DataEC50:  2nMAssay Description:Principle of the assay: The HTRF® assay kit was purchased from Cisbio-US, Inc. (Bedford, Mass.; Catalog #62AM4PEC). The HTRF® assay supported by the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstacyclin receptor(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM357272(2-(((1s,4s)-4-((5-(2- hydroxyethylthio)-4-(3- meth...)
Affinity DataEC50:  2nMAssay Description:The HTRF assay was carried out using a two-step protocol essentially according to the kit manufacturer's instructions, in 20 μL total volume...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent