BDBM35755 cis-1,2-diaminocyclohexane derivative, 8l

SMILES CN(C)C(=O)[C@H]1CC[C@H](NC(=O)c2[nH]c3ccc(F)cc3c2Cl)[C@@H](C1)NC(=O)c1nc2CCN(C)Cc2s1

InChI Key InChIKey=PRNHFCBYKORVPK-SOVGHPHASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 35755   

TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Sankyo

LigandPNGBDBM35755(cis-1,2-diaminocyclohexane derivative, 8l)
Affinity DataIC50:  5.70nMpH: 7.4 T: 2°CAssay Description:The in vitro anti-fXa activity was measured by using a chromogenic substrate S-2222 and human fXa. Aqueous DMSO or test compounds in aqueous DMSO and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed