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BDBM357739 AG-01-128/(I-202)::US10214530, Example 18

SMILES: CCN1c2c(n(c(n2)Cc3[nH]c4ccccc4n3)Cc5ccccc5)C(=O)NC1=O

InChI Key: InChIKey=KRRLVHYAVVYHJV-UHFFFAOYSA-N

Data: 4 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 357739
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tryptophan 5-hydroxylase 1 (Human)	BDBM357739 (AG-01-128/(I-202) \| US10214530, Example 18) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tryptophan 5-hydroxylase 2 (Human)	BDBM357739 (AG-01-128/(I-202) \| US10214530, Example 18) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tryptophan 5-hydroxylase 1 (Human)	BDBM357739 (AG-01-128/(I-202) \| US10214530, Example 18) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tryptophan 5-hydroxylase 2 (Human)	BDBM357739 (AG-01-128/(I-202) \| US10214530, Example 18) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair