BDBM357857 Aphthasol::US10214536, Amlexanox

SMILES: CC(C)c1ccc2c(c1)C(=O)c3cc(c(nc3O2)N)C(=O)O

InChI Key: InChIKey=SGRYPYWGNKJSDL-UHFFFAOYSA-N

Data: 10 IC50  1 Kd  1 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 357857   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase TBK1 (Human)	BDBM357857 (US10214536, Amlexanox | Aphthasol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM357857 (US10214536, Amlexanox | Aphthasol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM357857 (US10214536, Amlexanox | Aphthasol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.04E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM357857 (US10214536, Amlexanox | Aphthasol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM357857 (US10214536, Amlexanox | Aphthasol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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G-protein coupled receptor 35 (Human)	BDBM357857 (US10214536, Amlexanox | Aphthasol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit epsilon (Human)	BDBM357857 (US10214536, Amlexanox | Aphthasol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase TBK1 (Human)	BDBM357857 (US10214536, Amlexanox | Aphthasol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Serine/threonine-protein kinase TBK1 (Human)	BDBM357857 (US10214536, Amlexanox | Aphthasol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	851	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Inhibitor of nuclear factor kappa-B kinase subunit epsilon (Human)	BDBM357857 (US10214536, Amlexanox | Aphthasol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Transthyretin (Human)	BDBM357857 (US10214536, Amlexanox | Aphthasol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a
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G protein-coupled receptor kinase 5 (Mus musculus)	BDBM357857 (US10214536, Amlexanox | Aphthasol) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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