BDBM358 (2R,3R,4R,5R)-2,5-bis(benzyloxy)-3,4-dihydroxy-N,N'-bis[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]hexanediamide::1-Valine Methylamide deriv. 11::C2-symmetric compound 8::Diol-Based HIV-1 protease inhibitor 1::symmetric/asymmetric inhibitor 2

SMILES: O[C@H]([C@@H](O)[C@@H](OCc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12)[C@@H](OCc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12

InChI Key: InChIKey=UOHMQWQGAJAUGT-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 358   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM358 (symmetric/asymmetric inhibitor 2 | (2R,3R,4R,5R)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		0.200	-13.4	n/a	n/a	n/a	n/a	n/a	5.0	30
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Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM358 (symmetric/asymmetric inhibitor 2 | (2R,3R,4R,5R)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	-12.8	n/a	n/a	n/a	n/a	n/a	5.0	30
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Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM358 (symmetric/asymmetric inhibitor 2 | (2R,3R,4R,5R)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		1.22	-12.4	n/a	n/a	n/a	n/a	n/a	5.0	30
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Plasmepsin I (malaria parasite P. falciparum)	BDBM358 (symmetric/asymmetric inhibitor 2 | (2R,3R,4R,5R)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Plasmepsin II (Plasmodium falciparum)	BDBM358 (symmetric/asymmetric inhibitor 2 | (2R,3R,4R,5R)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		85	-9.54	n/a	n/a	n/a	n/a	n/a	4.5	22
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Cathepsin D (Human)	BDBM358 (symmetric/asymmetric inhibitor 2 | (2R,3R,4R,5R)-2...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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