BDBM358014 3-(4-amino-5-(1-(tetrahydro-2H-pyran- 4-yl)-1H-pyrazol-5-yl)pyrrolo[2,1-f] [1,2,4]triazin-7-yl)-5-fluoro-N-(3- hydroxy-2,2-dimethylpropyl)-N- methylbenzamide::US10214537, Example 83
SMILES CN(CC(C)(C)CO)C(=O)c1cc(F)cc(c1)-c1cc(-c2ccnn2C2CCOCC2)c2c(N)ncnn12
InChI Key InChIKey=KXSRMVBZHNRJLW-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 358014
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 6nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair