BDBM358452 1-{5-[4-amino-5-(1-methyl-1H- pyrazol-4-yl)pyrrolo[2,1-f][1,2,4] triazin-7-yl]-2-fluorophenyl}-4- cyclopropanecarbonyl-3,3- dimethylpiperazin-2-one::US10214537, Example 522

SMILES Cn1cc(cn1)-c1cc(-c2ccc(F)c(c2)N2CCN(C(=O)C3CC3)C(C)(C)C2=O)n2ncnc(N)c12

InChI Key InChIKey=GLXKIKPVDJRZEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 358452   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM358452(1-{5-[4-amino-5-(1-methyl-1H- pyrazol-4-yl)pyrrolo...)
Affinity DataIC50:  2nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent