BDBM358452 1-{5-[4-amino-5-(1-methyl-1H- pyrazol-4-yl)pyrrolo[2,1-f][1,2,4] triazin-7-yl]-2-fluorophenyl}-4- cyclopropanecarbonyl-3,3- dimethylpiperazin-2-one::US10214537, Example 522
SMILES Cn1cc(cn1)-c1cc(-c2ccc(F)c(c2)N2CCN(C(=O)C3CC3)C(C)(C)C2=O)n2ncnc(N)c12
InChI Key InChIKey=GLXKIKPVDJRZEB-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 358452
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 2nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair