BindingDB PrimarySearch

BDBM35847 (15S)-prostaglandin E2::(5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid::(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid::(E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid::CHEMBL548::DINOPROSTONE::PGE2::[3H]Dinoprostone::[3H]PGE2::[3H]Prostaglandin E2::prostaglandin E2

SMILES: CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O

InChI Key: InChIKey=XEYBRNLFEZDVAW-UHFFFAOYSA-N

Data: 49 KI 16 IC50 18 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 83 hits for monomerid = 35847
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin E2 receptor EP2 subtype (Rat)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Prostaglandin E2 receptor EP2 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP1 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP4 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Prostaglandin E2 receptor EP4 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.0200	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP4 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.583	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Prostaglandin E2 receptor EP2 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	331	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Prostaglandin E2 receptor EP2 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	9.30	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP2 subtype (Rat)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Prostaglandin E2 receptor EP4 subtype (Rat)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP3 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Prostaglandin E2 receptor EP4 subtype (Rat)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Prostaglandin E2 receptor EP4 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP3 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.940	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Prostaglandin E2 receptor EP2 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	37.7	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP1 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Prostaglandin E2 receptor EP4 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Prostaglandin E2 receptor EP4 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Prostaglandin E2 receptor EP4 subtype (Rat)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3.5	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP2 subtype (Rat)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP4 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP3 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
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Prostaglandin F2-alpha receptor (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP2 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.90	n/a	n/a	n/a	n/a
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Prostacyclin receptor (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	347	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	7.5	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3.70	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	346	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostacyclin receptor (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	2.10	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mouse)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	0.850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mouse)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin E2 receptor EP3 subtype (Bovine)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Human)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mouse)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mouse)	BDBM35847 (DINOPROSTONE \| [3H]Prostaglandin E2 \| prostaglandi...) Show SMILES Show InChI	GoogleScholar	UniChem	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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