BindingDB PrimarySearch

BDBM35909 2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide::2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide (hydroxy flutamide)::2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide(Hydroxyflutamide)::2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide::CHEMBL491::Eulexin::Hydroxyflutamide::OH-flutamide::Sch 16423::US9682960, OH-FLU::cid_91649::hydroxy-flutamide

SMILES: CC(C)(C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+](=O)[O-])O

InChI Key: InChIKey=YPQLFJODEKMJEF-UHFFFAOYSA-N

Data: 9 KI 24 IC50 1 EC50

PDB links: 8 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 34 hits for monomerid = 35909
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	7.2	23
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Mouse)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Mouse)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	224	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
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Progesterone receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Mouse)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Mouse)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	67	n/a	n/a	n/a	n/a	7.4	25
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Protein LANA1 (HHV-8)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Human)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Androgen receptor (Rat)	BDBM35909 (Eulexin \| 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...) Show SMILES Show InChI	GoogleScholar	UniChem	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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