BindingDB logo
myBDB logout

BDBM359212 US10221129, Example JB-22

SMILES: COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=HBHKKKMQYQJCAR-QFIPXVFZSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 359212   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Envelope glycoprotein gp160


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM359212
PNG
(US10221129, Example JB-22)
Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C24H25ClN4O5S/c1-29(20-12-14-21(34-2)15-13-20)23(30)22(16-17-6-4-3-5-7-17)26-24(31)28-35(32,33)27-19-10-8-18(25)9-11-19/h3-15,22,27H,16H2,1-2H3,(H2,26,28,31)/t22-/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 70n/an/an/an/a



ViiV HEALTHCARE UK (NO. 5) LIMITED

US Patent


Assay Description
HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...


US Patent US10221129 (2019)


BindingDB Entry DOI: 10.7270/Q2R213N8
More data for this
Ligand-Target Pair